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Managing chronic pain is difficult. It can take months or even years trying different medications to find the one that provides relief. Genetic factors impact how individuals respond to certain pain medications, and a simple DNA test can help you know exactly how your body will react. PainDX lets your doctor know which medications will work (and which ones could cause dangerous side effects) before they write a prescription. The PainDX test covers 34 pain medications, see the full list.

To get the PainDX test, order a kit and and bring it to your doctor. 

Buy Kit - $250



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Pain management specifically for you.

Chronic pain is the most common cause of long-term disability in the United States. Managing pain medications with GnomeDX reduces "trial and error", the risk of negative side effects and the time spent finding the right medication for your recovery. 

With PainDX, you will learn:

  • How your body metabolizes 34 common pain medications

  • Which medications may cause negative side effects

  • Which medications may require higher or lower dosages



How it works

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Order a kit online for $350. We'll send it to your home.

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Talk to your doctor. Don’t have a doctor?

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Swab the inside of your cheek to gather your DNA sample.

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Send your sample back in the mail with a pre-filled label.

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We'll test your DNA and send you back your results.

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Review results with your doctor and make an plan for your health.

Who should take PainDX? 

If you’ve been suffering from uncontrolled pain or have tried multiple pain medications without relief, GnomeDX's PainDX test can help your doctor prescribe the most effective medication based on your unique genetic profile. It also helps doctors avoid prescribing medications that won’t work for you or may cause serious side effects. PainDX is helpful for people who suffer from chronic pain, such as lower back pain, cancer, arthritis, and neurogenic painGnomeDX reduces the time it takes to find the right medication, bringing you faster relief.

Don’t all pain medications work?

Some people do not get any pain relief from normal doses of commonly-prescribed pain medications, while others can overdose after taking the prescribed amount. The wide range of responses to pain medication makes it difficult for a physician to determine what medication will work best for you. To avoid negative side effects and make sure you take a medication that will work, your doctor can use the PainDX test to see which of several FDA-approved medications will work for you.

How much does painDX cost?

Our pricing is simple - all tests require an upfront payment of $250.

Although initial online payment is required before the test can be processed, you can request to submit a claim to insurance or Medicare to be reimbursed. The forms required to submit to insurance are included in the GnomeDX kit and are labeled clearly. Once received, we will review your insurance information and GnomeDX will submit the claim to insurance. Like any other lab test, insurance coverage and reimbursement policies vary by plan and provider.

The GnomeDX PainDX maximum self-pay price is $250.

What Medicines are covered by PainDX?

PainDX covers 34 pain medications. 

Drugs include opiods such as codeine, morphine (MS Contin®), oxycodone (Percocet®, Oxycontin®), and tramadol (Ultram®). The test also covers NSAIDs like celecoxib (Celebrex®) and even ibuprofen (Advil®, Motrin®).

The Science Of Testing

Read more about the science of genetic testing

Genes Included

The PainDX test covers 7 genes