Pharmacogenetic Resources: PharmGKB and Clinical Pharmacogenetics and Implementation Consortium

PharmGKB is an online resource that originally began in 2000 as an NIH-funded project to store deposited genotype and phenotype information from research sites across the United States. What was found, though, was a an interest not only from researchers, but "students, pharmacists, genetics counselors clinicians, and the public", who wanted peer-reviewed evidence of which genetic variants appeared to impact certain drug responses. PharmGKB and the CPIC are the foremost resources for the clinical interpretation and validation of known drug-gene interactions, and the article below further details the methods in which this is demonstrated. Read below for more on what operates as the clinically-validated foundation of personalized medicine.